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Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators

Unique chemical methodology enables the synthesis of innovative and diverse scaffolds and chemotypes and allows access to previously unexplored “chemical space.” Compound collections based on such new synthetic methods can provide small-molecule probes of proteins and/or pathways whose functions are...

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書誌詳細
主要な著者: Huryn, Donna M., Brodsky, Jeffrey L., Brummond, Kay M., Chambers, Peter G., Eyer, Benjamin, Ireland, Alex W., Kawasumi, Masaoki, LaPorte, Matthew G., Lloyd, Kayla, Manteau, Baptiste, Nghiem, Paul, Quade, Bettina, Seguin, Sandlin P., Wipf, Peter
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084104/
https://ncbi.nlm.nih.gov/pubmed/21502524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015251108
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