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Large-scale characterization of peptide-MHC binding landscapes with structural simulations

Class I major histocompatibility complex proteins play a critical role in the adaptive immune system by binding to peptides derived from cytosolic proteins and presenting them on the cell surface for surveillance by T cells. The varied peptide binding specificity of these highly polymorphic molecule...

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Autori principali: Yanover, Chen, Bradley, Philip
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084072/
https://ncbi.nlm.nih.gov/pubmed/21478437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018165108
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