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Large-scale characterization of peptide-MHC binding landscapes with structural simulations
Class I major histocompatibility complex proteins play a critical role in the adaptive immune system by binding to peptides derived from cytosolic proteins and presenting them on the cell surface for surveillance by T cells. The varied peptide binding specificity of these highly polymorphic molecule...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084072/ https://ncbi.nlm.nih.gov/pubmed/21478437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018165108 |
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