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Extensive protein and DNA backbone sampling improves structure-based specificity prediction for C(2)H(2) zinc fingers

Sequence-specific DNA recognition by gene regulatory proteins is critical for proper cellular functioning. The ability to predict the DNA binding preferences of these regulatory proteins from their amino acid sequence would greatly aid in reconstruction of their regulatory interactions. Structural m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yanover, Chen, Bradley, Philip
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113574/
https://ncbi.nlm.nih.gov/pubmed/21343182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr048
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