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Extensive protein and DNA backbone sampling improves structure-based specificity prediction for C(2)H(2) zinc fingers
Sequence-specific DNA recognition by gene regulatory proteins is critical for proper cellular functioning. The ability to predict the DNA binding preferences of these regulatory proteins from their amino acid sequence would greatly aid in reconstruction of their regulatory interactions. Structural m...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113574/ https://ncbi.nlm.nih.gov/pubmed/21343182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr048 |
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