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A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity
Development of an accurate protein–DNA recognition code that can predict DNA specificity from protein sequence is a central problem in biology. C(2)H(2) zinc fingers constitute by far the largest family of DNA binding domains and their binding specificity has been studied intensively. However, despi...
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Publié dans: | Nucleic Acids Res |
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Auteurs principaux: | , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Oxford University Press
2015
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4627083/ https://ncbi.nlm.nih.gov/pubmed/26384429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv919 |
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