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Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding
BACKGROUND: The C2H2 zinc finger (C2H2-ZF) is the most numerous protein domain in many metazoans, but is not as frequent or diverse in other eukaryotes. The biochemical and evolutionary mechanisms that underlie the diversity of this DNA-binding domain exclusively in metazoans are, however, mostly un...
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| Publicado no: | Genome Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588721/ https://ncbi.nlm.nih.gov/pubmed/28877740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1287-y |
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