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Specific penetration and accumulation of a homing peptide within atherosclerotic plaques of apolipoprotein E-deficient mice

The ability to selectively deliver compounds into atherosclerotic plaques would greatly benefit the detection and treatment of atherosclerotic disease. We describe such a delivery system based on a 9-amino acid cyclic peptide, LyP-1. LyP-1 was originally identified as a tumor-homing peptide that spe...

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Autors principals: Hamzah, Juliana, Kotamraju, Venkata R., Seo, Jai W., Agemy, Lilach, Fogal, Valentina, Mahakian, Lisa M., Peters, David, Roth, Lise, Gagnon, M. Karen J., Ferrara, Katherine W., Ruoslahti, Erkki
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084060/
https://ncbi.nlm.nih.gov/pubmed/21482787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104540108
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