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The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65–Prp19 complex
Pre-mRNA splicing is frequently coupled to transcription by RNA polymerase II (RNAPII). This coupling requires the C-terminal domain of the RNAPII largest subunit (CTD), although the underlying mechanism is poorly understood. Using a biochemical complementation assay, we previously identified an act...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084030/ https://ncbi.nlm.nih.gov/pubmed/21536736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2038011 |
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