Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3′-splice site recognition

Recognition of the 3′-splice site is a key step in pre-mRNA splicing and accomplished by a dynamic complex comprising splicing factor 1 (SF1) and the U2 snRNP auxiliary factor 65-kDa subunit (U2AF65). Both proteins mediate protein–protein and protein–RNA interactions for cooperative RNA-binding duri...

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Main Authors: Zhang, Yun, Madl, Tobias, Bagdiul, Ivona, Kern, Thomas, Kang, Hyun-Seo, Zou, Peijian, Mäusbacher, Nina, Sieber, Stephan A., Krämer, Angela, Sattler, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553976/
https://ncbi.nlm.nih.gov/pubmed/23175611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1097
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