Activity-based protein profiling

Por Sieber, Stephan A., Breinbauer, R.
Publicado em c201

Learning from Nature's Drug Factories: Nonribosomal Synthesis of Macrocyclic Peptides

Por Sieber, Stephan A., Marahiel, Mohamed A.
Publicado em 2003

Insights into Structural Network Responsible for Oligomerization and Activity of Bacterial Virulence Regulator Caseinolytic Protease P (ClpP) Protein

Por Gersch, Malte, List, Anja, Groll, Michael, Sieber, Stephan A.
Publicado em 2012

Synthesis of ramariolide natural products and discovery of their targets in mycobacteria

Por Lehmann, Johannes, Richers, Johannes, Pöthig, Alexander, Sieber, Stephan A.
Publicado no Chem Commun (Camb) (2017)

Proteomic profiling of metalloprotease activities with cocktails of active-site probes

Por Sieber, Stephan A, Niessen, Sherry, Hoover, Heather S, Cravatt, Benjamin F
Publicado em 2006

Target discovery of acivicin in cancer cells elucidates its mechanism of growth inhibition

Por Kreuzer, Johannes, Bach, Nina C., Forler, Daniel, Sieber, Stephan A.
Publicado no Chem Sci (2015)

A Chemical Proteomic Analysis of Illudin‐Interacting Proteins

Por Le, Philipp, Nodwell, Matthew B., Eirich, Jürgen, Sieber, Stephan A.
Publicado no Chemistry (2019)

Total Synthesis of the Cyclic Depsipeptide Vioprolide D via its (Z)‐Diastereoisomer

Por Grab, Hanusch A., Kirsch, Volker C., Sieber, Stephan A., Bach, Thorsten
Publicado no Angew Chem Int Ed Engl (2020)

Customizing Functionalized Cofactor Mimics to Study the Human Pyridoxal 5′-Phosphate-Binding Proteome

Por Fux, Anja, Pfanzelt, Martin, Kirsch, Volker C., Hoegl, Annabelle, Sieber, Stephan A.
Publicado no Cell Chem Biol (2019)

Acyldepsipeptide Probes Facilitate Specific Detection of Caseinolytic Protease P Independent of Its Oligomeric and Activity State

Por Eyermann, Barbara, Meixner, Maximilian, Brötz‐Oesterhelt, Heike, Antes, Iris, Sieber, Stephan A.
Publicado no Chembiochem (2020)

Activity-Based Probes for Studying the Activity of Flavin-Dependent Oxidases and for the Protein Target Profiling of Monoamine Oxidase Inhibitors**

Por Krysiak, Joanna M, Kreuzer, Johannes, Macheroux, Peter, Hermetter, Albin, Sieber, Stephan A, Breinbauer, Rolf
Publicado em 2012

A Pronucleotide Probe for Live‐Cell Imaging of Protein AMPylation

Por Kielkowski, Pavel, Buchsbaum, Isabel Y., Becker, Tobias, Bach, Kathrin, Cappello, Silvia, Sieber, Stephan A.
Publicado no Chembiochem (2020)

Insights into ClpXP proteolysis: heterooligomerization and partial deactivation enhance chaperone affinity and substrate turnover in Listeria monocytogenes

Por Balogh, Dóra, Dahmen, Maria, Stahl, Matthias, Poreba, Marcin, Gersch, Malte, Drag, Marcin, Sieber, Stephan A.
Publicado no Chem Sci (2017)

Comparative Target Analysis of Chlorinated Biphenyl Antimicrobials Highlights MenG as a Molecular Target of Triclocarban

Por Macsics, Robert, Hackl, Mathias W., Fetzer, Christian, Mostert, Dietrich, Bender, Jennifer, Layer, Franziska, Sieber, Stephan A.
Publicado no Appl Environ Microbiol (2020)

Surface topology affects wetting behavior of Bacillus subtilis biofilms

Por Werb, Moritz, Falcón García, Carolina, Bach, Nina C., Grumbein, Stefan, Sieber, Stephan A., Opitz, Madeleine, Lieleg, Oliver
Publicado no NPJ Biofilms Microbiomes (2017)

Dual Inhibitor of Staphylococcus aureus Virulence and Biofilm Attenuates Expression of Major Toxins and Adhesins

Por Hofbauer, Barbara, Vomacka, Jan, Stahl, Matthias, Korotkov, Vadim S., Jennings, Megan C., Wuest, William M., Sieber, Stephan A.
Publicado no Biochemistry (2018)

FICD activity and AMPylation remodelling modulate human neurogenesis

Por Kielkowski, Pavel, Buchsbaum, Isabel Y., Kirsch, Volker C., Bach, Nina C., Drukker, Micha, Cappello, Silvia, Sieber, Stephan A.
Publicado no Nat Commun (2020)

Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad

Por Zeiler, Evelyn, List, Anja, Alte, Ferdinand, Gersch, Malte, Wachtel, Rudolf, Poreba, Marcin, Drag, Marcin, Groll, Michael, Sieber, Stephan A.
Publicado em 2013

The Cytotoxic Natural Product Vioprolide A Targets Nucleolar Protein 14, Which Is Essential for Ribosome Biogenesis

Por Kirsch, Volker C., Orgler, Christina, Braig, Simone, Jeremias, Irmela, Auerbach, David, Müller, Rolf, Vollmar, Angelika M., Sieber, Stephan A.
Publicado no Angew Chem Int Ed Engl (2019)

A chemical compound inhibiting the Aha1–Hsp90 chaperone complex

Por Stiegler, Sandrine C., Rübbelke, Martin, Korotkov, Vadim S., Weiwad, Matthias, John, Christine, Fischer, Gunter, Sieber, Stephan A., Sattler, Michael, Buchner, Johannes
Publicado no J Biol Chem (2017)