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SF1 Phosphorylation Enhances Specific Binding to U2AF(65) and Reduces Binding to 3′-Splice-Site RNA
Splicing factor 1 (SF1) recognizes 3′ splice sites of the major class of introns as a ternary complex with U2AF(65) and U2AF(35) splicing factors. A conserved SPSP motif in a coiled-coil domain of SF1 is highly phosphorylated in proliferating human cells and is required for cell proliferation. The U...
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| Vydáno v: | Biophys J |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Biophysical Society
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5192697/ https://ncbi.nlm.nih.gov/pubmed/28002734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.11.007 |
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