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RNA Induces Conformational Changes in the SF1/U2AF(65) Splicing Factor Complex
Spliceosomes assemble on pre-mRNA splice sites through a series of dynamic ribonucleoprotein complexes, yet the nature of the conformational changes remains unclear. Splicing Factor 1 (SF1) and U2 Auxiliary Factor (U2AF(65)) cooperatively recognize the 3’ splice site during the initial stages of pre...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037027/ https://ncbi.nlm.nih.gov/pubmed/21146534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.11.054 |
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