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Solution Conformation and Thermodynamic Characteristics of RNA Binding by the Splicing Factor U2AF(65)
The U2 auxiliary factor large subunit (U2AF(65)) is an essential pre-mRNA splicing factor for the initial stages of spliceosome assembly. Tandem RNA recognition motifs (RRM)s of U2AF(65) recognize polypyrimidine tract signals adjacent to 3′ splice sites. Despite the central importance of U2AF(65) fo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586248/ https://ncbi.nlm.nih.gov/pubmed/18842594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806297200 |
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