Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer

Human cancer cells frequently have regions of their DNA hypermethylated, which results in transcriptional silencing of affected genes and promotion of tumor formation. However, it is still unknown whether cancer-associated aberrant DNA methylation is targeted to specific genomic regions, whether thi...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Steine, Eveline J., Ehrich, Mathias, Bell, George W., Raj, Arjun, Reddy, Seshamma, van Oudenaarden, Alexander, Jaenisch, Rudolf, Linhart, Heinz G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2011
Предметы:
Brief Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083798/
https://ncbi.nlm.nih.gov/pubmed/21490393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43169
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы