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Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer
Human cancer cells frequently have regions of their DNA hypermethylated, which results in transcriptional silencing of affected genes and promotion of tumor formation. However, it is still unknown whether cancer-associated aberrant DNA methylation is targeted to specific genomic regions, whether thi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083798/ https://ncbi.nlm.nih.gov/pubmed/21490393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43169 |
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