Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene
Previous attempts to express functional DNA cytosine methyltransferase (EC 2.1.1.37) in cells transfected with the available Dnmt cDNAs have met with little or no success. We show that the published Dnmt sequence encodes an amino terminal-truncated protein that is tolerated only at very low levels w...
Furkejuvvon:
| Publikašuvnnas: | Proc Natl Acad Sci U S A |
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| Váldodahkkit: | , , , , |
| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
National Academy of Sciences
1996
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| Fáttát: | |
| Liŋkkat: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24021/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8917520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.23.12920 |
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