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Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene

Previous attempts to express functional DNA cytosine methyltransferase (EC 2.1.1.37) in cells transfected with the available Dnmt cDNAs have met with little or no success. We show that the published Dnmt sequence encodes an amino terminal-truncated protein that is tolerated only at very low levels w...

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Bibliografski detalji
Glavni autori: Tucker, Kerry Lee, Talbot, Dale, Lee, Min Ae, Leonhardt, Heinrich, Jaenisch, Rudolf
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1996
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC24021/
https://ncbi.nlm.nih.gov/pubmed/8917520
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