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Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis

Genome-wide DNA hypomethylation and concomitant promoter-specific tumor suppressor gene hypermethylation are among the most common molecular alterations in human neoplasia. Consistent with the notion that both promoter hypermethylation and genome-wide hypomethylation are functionally important in tu...

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Detalhes bibliográficos
Main Authors: Yamada, Yasuhiro, Jackson-Grusby, Laurie, Linhart, Heinz, Meissner, Alex, Eden, Amir, Lin, Haijiang, Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224663/
https://ncbi.nlm.nih.gov/pubmed/16174748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506612102
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