Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

Autophagy is a bulk protein degradation system that likely plays an important role in normal proximal tubule function and recovery from acute ischemic kidney injury. Using conditional Atg5 gene deletion to eliminate autophagy in the proximal tubule, we determined whether autophagy prevents accumulat...

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Hlavní autoři: Kimura, Tomonori, Takabatake, Yoshitsugu, Takahashi, Atsushi, Kaimori, Jun-ya, Matsui, Isao, Namba, Tomoko, Kitamura, Harumi, Niimura, Fumio, Matsusaka, Taiji, Soga, Tomoyoshi, Rakugi, Hiromi, Isaka, Yoshitaka
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2011
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083312/
https://ncbi.nlm.nih.gov/pubmed/21493778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010070705
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