Autophagic Clearance of Mitochondria in the Kidney Copes with Metabolic Acidosis

Metabolic acidosis, a common complication of CKD, causes mitochondrial stress by undefined mechanisms. Selective autophagy of impaired mitochondria, called mitophagy, contributes toward maintaining cellular homeostasis in various settings. We hypothesized that mitophagy is involved in proximal tubul...

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Hlavní autoři: Namba, Tomoko, Takabatake, Yoshitsugu, Kimura, Tomonori, Takahashi, Atsushi, Yamamoto, Takeshi, Matsuda, Jun, Kitamura, Harumi, Niimura, Fumio, Matsusaka, Taiji, Iwatani, Hirotsugu, Matsui, Isao, Kaimori, Junya, Kioka, Hidetaka, Isaka, Yoshitaka, Rakugi, Hiromi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2014
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178439/
https://ncbi.nlm.nih.gov/pubmed/24700866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013090986
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