Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

Autophagy is a bulk protein degradation system that likely plays an important role in normal proximal tubule function and recovery from acute ischemic kidney injury. Using conditional Atg5 gene deletion to eliminate autophagy in the proximal tubule, we determined whether autophagy prevents accumulat...

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Bibliographische Detailangaben
Hauptverfasser: Kimura, Tomonori, Takabatake, Yoshitsugu, Takahashi, Atsushi, Kaimori, Jun-ya, Matsui, Isao, Namba, Tomoko, Kitamura, Harumi, Niimura, Fumio, Matsusaka, Taiji, Soga, Tomoyoshi, Rakugi, Hiromi, Isaka, Yoshitaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2011
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083312/
https://ncbi.nlm.nih.gov/pubmed/21493778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010070705
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