Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

Autophagy is a bulk protein degradation system that likely plays an important role in normal proximal tubule function and recovery from acute ischemic kidney injury. Using conditional Atg5 gene deletion to eliminate autophagy in the proximal tubule, we determined whether autophagy prevents accumulat...

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Dettagli Bibliografici
Autori principali: Kimura, Tomonori, Takabatake, Yoshitsugu, Takahashi, Atsushi, Kaimori, Jun-ya, Matsui, Isao, Namba, Tomoko, Kitamura, Harumi, Niimura, Fumio, Matsusaka, Taiji, Soga, Tomoyoshi, Rakugi, Hiromi, Isaka, Yoshitaka
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2011
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083312/
https://ncbi.nlm.nih.gov/pubmed/21493778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010070705
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