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Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

Autophagy is a bulk protein degradation system that likely plays an important role in normal proximal tubule function and recovery from acute ischemic kidney injury. Using conditional Atg5 gene deletion to eliminate autophagy in the proximal tubule, we determined whether autophagy prevents accumulat...

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Bibliografiske detaljer
Main Authors: Kimura, Tomonori, Takabatake, Yoshitsugu, Takahashi, Atsushi, Kaimori, Jun-ya, Matsui, Isao, Namba, Tomoko, Kitamura, Harumi, Niimura, Fumio, Matsusaka, Taiji, Soga, Tomoyoshi, Rakugi, Hiromi, Isaka, Yoshitaka
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083312/
https://ncbi.nlm.nih.gov/pubmed/21493778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010070705
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