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Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes

Somatic genome rearrangements are thought to play important roles in cancer development. We optimized a long-span paired-end-tag (PET) sequencing approach using 10-Kb genomic DNA inserts to study human genome structural variations (SVs). The use of a 10-Kb insert size allows the identification of br...

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Detalhes bibliográficos
Main Authors: Hillmer, Axel M., Yao, Fei, Inaki, Koichiro, Lee, Wah Heng, Ariyaratne, Pramila N., Teo, Audrey S.M., Woo, Xing Yi, Zhang, Zhenshui, Zhao, Hao, Ukil, Leena, Chen, Jieqi P., Zhu, Feng, So, Jimmy B.Y., Salto-Tellez, Manuel, Poh, Wan Ting, Zawack, Kelson F.B., Nagarajan, Niranjan, Gao, Song, Li, Guoliang, Kumar, Vikrant, Lim, Hui Ping J., Sia, Yee Yen, Chan, Chee Seng, Leong, See Ting, Neo, Say Chuan, Choi, Poh Sum D., Thoreau, Hervé, Tan, Patrick B.O., Shahab, Atif, Ruan, Xiaoan, Bergh, Jonas, Hall, Per, Cacheux-Rataboul, Valère, Wei, Chia-Lin, Yeoh, Khay Guan, Sung, Wing-Kin, Bourque, Guillaume, Liu, Edison T., Ruan, Yijun
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083083/
https://ncbi.nlm.nih.gov/pubmed/21467267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.113555.110
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