Long Span DNA Paired-End-Tag (DNA-PET) Sequencing Strategy for the Interrogation of Genomic Structural Mutations and Fusion-Point-Guided Reconstruction of Amplicons

Structural variations (SVs) contribute significantly to the variability of the human genome and extensive genomic rearrangements are a hallmark of cancer. While genomic DNA paired-end-tag (DNA-PET) sequencing is an attractive approach to identify genomic SVs, the current application of PET sequencin...

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Hlavní autoři: Yao, Fei, Ariyaratne, Pramila N., Hillmer, Axel M., Lee, Wah Heng, Li, Guoliang, Teo, Audrey S. M., Woo, Xing Yi, Zhang, Zhenshui, Chen, Jieqi P., Poh, Wan Ting, Zawack, Kelson F. B., Chan, Chee Seng, Leong, See Ting, Neo, Say Chuan, Choi, Poh Sum D., Gao, Song, Nagarajan, Niranjan, Thoreau, Hervé, Shahab, Atif, Ruan, Xiaoan, Cacheux-Rataboul, Valère, Wei, Chia-Lin, Bourque, Guillaume, Sung, Wing-Kin, Liu, Edison T., Ruan, Yijun
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461012/
https://ncbi.nlm.nih.gov/pubmed/23029419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046152
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