Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone

Genome-scale mapping of pre-replication complex proteins has not been reported in mammalian cells. Poor enrichment of these proteins at specific sites may be due to dispersed binding, poor epitope availability or cell cycle stage-specific binding. Here, we have mapped sites of biotin-tagged ORC and...

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Bibliografiske detaljer
Main Authors: Lubelsky, Yoav, Sasaki, Takayo, Kuipers, Marjorie A., Lucas, Isabelle, Le Beau, Michelle M., Carignon, Sandra, Debatisse, Michelle, Prinz, Joseph A., Dennis, Jonathan H., Gilbert, David M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082903/
https://ncbi.nlm.nih.gov/pubmed/21148149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1276
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