Caloric Restriction and Growth Hormone Receptor Knockout: Effects on Expression of Genes Involved in Insulin Action in the Heart

Blockade of growth hormone (GH), decreased insulin-like growth factor-1 (IGF1) action and increased insulin sensitivity are associated with life extension and an apparent slowing of the aging process. We examined expression of genes involved in insulin action, IR, IRS1, IRS2, IGF1, IGF1R, GLUT4, PPA...

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Detalhes bibliográficos
Main Authors: Masternak, Michal M., Al-Regaiey, Khalid A, Del Rosario Lim, Marc Michael, Jimenez-Ortega, Vanesa, Panici, Jacob A, Bonkowski, Michael S., Kopchick, John J., Wang, Zhihui, Bartke, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082456/
https://ncbi.nlm.nih.gov/pubmed/16524678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2006.01.009
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