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Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction
Reduced intake of nutrients [calorie restriction (CR)] extends longevity in organisms ranging from yeast to mammals. Mutations affecting somatotropic, insulin, or homologous signaling pathways can increase life span in worms, flies, and mice, and there is considerable evidence that reduced secretion...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458512/ https://ncbi.nlm.nih.gov/pubmed/16682650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600161103 |
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