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The Growth Hormone Receptor Gene-Disrupted (GHR-KO) Mouse Fails to Respond to an Intermittent Fasting (IF) Diet

The interaction of longevity-conferring genes with longevity-conferring diets is poorly understood. The growth hormone receptor gene-disrupted (GHR-KO) mouse is long-lived; and this longevity is not responsive to 30% caloric restriction (CR), in contrast to wild-type animals from the same strain. To...

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Detalhes bibliográficos
Main Authors: Arum, Oge, Bonkowski, Michael S., Rocha, Juliana S., Bartke, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783987/
https://ncbi.nlm.nih.gov/pubmed/19747233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2009.00520.x
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