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Selective Enhancement of Nucleases by Polyvalent DNA-Functionalized Gold Nanoparticles
We demonstrate that polyvalent DNA-functionalized gold nanoparticles (DNA-Au NPs) selectively enhance Ribonuclease H (RNase H) activity, while inhibiting most biologically relevant nucleases. This combination of properties is particularly interesting in the context of gene regulation, since high RNa...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081637/ https://ncbi.nlm.nih.gov/pubmed/21268581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja110833r |
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