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Transfection of pancreatic islets using polyvalent DNA-functionalized gold nanoparticles

BACKGROUND: Transplantation of pancreatic islets is an effective treatment for select patients with type 1 diabetes. Improved cellular therapy results may be realized by altering the gene expression profile of transplanted islets. Current viral and non-viral vectors used to introduce nucleic acids f...

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Detalhes bibliográficos
Main Authors: Rink, Jonathan S., McMahon, Kaylin M., Chen, Xiaojuan, Mirkin, Chad A., Thaxton, C. Shad, Kaufman, Dixon B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150467/
https://ncbi.nlm.nih.gov/pubmed/20633730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2010.05.013
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