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Knockdown of Intra-Islet IKKβ by Spherical Nucleic Acid Conjugates Prevents Cytokine-Induced Injury and Enhances Graft Survival()
INTRODUCTION: The efficiency of islet graft survival following intra-portal implantation is compromised by host innate immune responses and the production of pro-inflammatory cytokines that cause acute cellular injury. This reaction activates intra-islet NF-κB causing production of gene products tha...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839058/ https://ncbi.nlm.nih.gov/pubmed/24247900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3182a4190e |
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