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Conjugation Chemistry-Dependent T-Cell Activation with Spherical Nucleic Acids
Spherical nucleic acids (SNAs) can be potent sequence-specific stimulators of antigen presenting cells (APCs). When loaded with peptide antigens, they can be used to activate the immune system to train T-cells to specifically kill cancer cells. Herein, the role of peptide chemical conjugation to the...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5831183/ https://ncbi.nlm.nih.gov/pubmed/29356509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b12579 |
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