Development of Spherical Nucleic Acids for Prostate Cancer Immunotherapy

Although the strategy of therapeutic vaccination for the treatment of prostate cancer has advanced to and is available in the clinic (Sipuleucel-T), the efficacy of such therapy remains limited. Here, we develop Immunostimulatory Spherical Nucleic Acid (IS-SNA) nanostructures comprised of CpG oligon...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Qin, Lei, Wang, Shuya, Dominguez, Donye, Long, Alan, Chen, Siqi, Fan, Jie, Ahn, Jihae, Skakuj, Kacper, Huang, Ziyin, Lee, Andrew, Mirkin, Chad, Zhang, Bin
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362897/
https://ncbi.nlm.nih.gov/pubmed/32733447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01333
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