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Mechanism for the endocytosis of spherical nucleic acid nanoparticle conjugates

Intracellular delivery of nucleic acids as gene regulation agents typically requires the use of cationic carriers or viral vectors, yet issues related to cellular toxicity or immune responses hamper their attractiveness as therapeutic candidates. The discovery that spherical nucleic acids (SNAs), po...

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Detalhes bibliográficos
Main Authors: Choi, Chung Hang J., Hao, Liangliang, Narayan, Suguna P., Auyeung, Evelyn, Mirkin, Chad A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651452/
https://ncbi.nlm.nih.gov/pubmed/23613589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305804110
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