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Mechanism for the endocytosis of spherical nucleic acid nanoparticle conjugates

Intracellular delivery of nucleic acids as gene regulation agents typically requires the use of cationic carriers or viral vectors, yet issues related to cellular toxicity or immune responses hamper their attractiveness as therapeutic candidates. The discovery that spherical nucleic acids (SNAs), po...

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Détails bibliographiques
Auteurs principaux: Choi, Chung Hang J., Hao, Liangliang, Narayan, Suguna P., Auyeung, Evelyn, Mirkin, Chad A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651452/
https://ncbi.nlm.nih.gov/pubmed/23613589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305804110
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