Spherical Nucleic Acids as a Divergent Platform for Synthesizing RNA–Nanoparticle Conjugates through Enzymatic Ligation

[Image: see text] Herein, we describe a rapid, divergent method for using spherical nucleic acids (SNAs) as a universal platform for attaching RNA to DNA-modified nanoparticles using enzyme-mediated techniques. This approach provides a sequence-specific method for the covalent attachment of one or m...

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Bibliographic Details
Main Authors: Rouge, Jessica L., Hao, Liangliang, Wu, Xiaochen A., Briley, William E., Mirkin, Chad A.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174098/
https://ncbi.nlm.nih.gov/pubmed/25144723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn503601s
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