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Ribozyme-Spherical Nucleic Acids

Ribozymes are highly structured RNA sequences that can be tailored to recognize and cleave specific stretches of mRNA. Their current therapeutic efficacy remains low due to their large size and structural instability compared to shorter therapeutically relevant RNA such as small interfering RNA (siR...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Chem Soc
Prif Awduron: Rouge, Jessica L., Sita, Timothy L., Hao, Liangliang, Kouri, Fotini M., Briley, William E., Stegh, Alexander H., Mirkin, Chad A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666730/
https://ncbi.nlm.nih.gov/pubmed/26271335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b07104
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