Immunomodulatory spherical nucleic acids

Immunomodulatory nucleic acids have extraordinary promise for treating disease, yet clinical progress has been limited by a lack of tools to safely increase activity in patients. Immunomodulatory nucleic acids act by agonizing or antagonizing endosomal toll-like receptors (TLR3, TLR7/8, and TLR9), p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Radovic-Moreno, Aleksandar F., Chernyak, Natalia, Mader, Christopher C., Nallagatla, Subbarao, Kang, Richard S., Hao, Liangliang, Walker, David A., Halo, Tiffany L., Merkel, Timothy J., Rische, Clayton H., Anantatmula, Sagar, Burkhart, Merideth, Mirkin, Chad A., Gryaznov, Sergei M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Physical Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386353/
https://ncbi.nlm.nih.gov/pubmed/25775582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502850112
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