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Spherical Nucleic Acid Nanoparticle Conjugates Enhance G-Quadruplex Formation and Increase Serum Protein Interactions

To understand the effect of three-dimensional oligonucleotide structure on protein corona formation, we studied the identity and quantity of human serum proteins that bind to spherical nucleic acid (SNA) nanoparticle conjugates. SNAs exhibit cellular uptake properties that are remarkably different f...

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Publicado en:Angew Chem Int Ed Engl
Main Authors: Chinen, Alyssa B., Guan, Chenxia M., Mirkin, Chad A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314381/
https://ncbi.nlm.nih.gov/pubmed/25393322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201409211
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