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The Impact of Protein Corona Formation on the Macrophage Cellular Uptake and Biodistribution of Spherical Nucleic Acids

The effect of serum protein adsorption on the biological fate of Spherical Nucleic Acids (SNAs) is investigated. Through a proteomic analysis, it is shown that G-quadruplexes templated on the surface of a gold nanoparticle in the form of SNAs mediate the formation of a protein corona that is rich in...

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Publicado en:Small
Main Authors: Chinen, Alyssa B., Guan, Chenxia M., Ko, Caroline H., Mirkin, Chad A.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493144/
https://ncbi.nlm.nih.gov/pubmed/28196309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201603847
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