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Methods for the Analysis of High Precision Differential Hydrogen Deuterium Exchange Data

Hydrogen/deuterium exchange (HDX) mass spectrometry has been widely applied to the characterization of protein dynamics. More recently, differential HDX has been shown to be effective for the characterization of ligand binding. Previously we have described a fully automated HDX system for use as a l...

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Main Authors: Chalmers, Michael J., Pascal, Bruce D., Willis, Scooter, Zhang, Jun, Iturria, Stephen J., Dodge, Jeffery A., Griffin, Patrick R.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081588/
https://ncbi.nlm.nih.gov/pubmed/21528013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2010.08.002
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