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Rapid Temporal Control of Foxp3 Protein Degradation by Sirtuin-1
Maintenance of Foxp3 protein expression in regulatory T cells (Treg) is crucial for a balanced immune response. We have previously demonstrated that Foxp3 protein stability can be regulated through acetylation, however the specific mechanisms underlying this observation remain unclear. Here we demon...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080399/ https://ncbi.nlm.nih.gov/pubmed/21533107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019047 |
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