The forkhead transcription factor FOXP1 represses human plasma cell differentiation

Expression of the forkhead transcription factor FOXP1 is essential for early B-cell development, whereas downregulation of FOXP1 at the germinal center (GC) stage is required for GC B-cell function. Aberrantly high FOXP1 expression is frequently observed in diffuse large B-cell lymphoma and mucosa-a...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: van Keimpema, Martine, Grüneberg, Leonie J., Mokry, Michal, van Boxtel, Ruben, van Zelm, Menno C., Coffer, Paul, Pals, Steven T., Spaargaren, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626252/
https://ncbi.nlm.nih.gov/pubmed/26289642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-02-626176
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