The small FOXP1 isoform predominantly expressed in activated B cell-like diffuse large B-cell lymphoma and full-length FOXP1 exert similar oncogenic and transcriptional activity in human B cells

The forkhead transcription factor FOXP1 is generally regarded as an oncogene in activated B cell-like diffuse large B-cell lymphoma. Previous studies have suggested that a small isoform of FOXP1 rather than full-length FOXP1, may possess this oncogenic activity. Corroborating those studies, we herei...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: van Keimpema, Martine, Grüneberg, Leonie J., Schilder-Tol, Esther J.M., Oud, Monique E.C.M., Beuling, Esther A., Hensbergen, Paul J., de Jong, Johann, Pals, Steven T., Spaargaren, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394978/
https://ncbi.nlm.nih.gov/pubmed/27909217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.156455
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