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MDC1 collaborates with TopBP1 in DNA replication checkpoint control
Human TopBP1 is a major player in the control of the DNA replication checkpoint. In this study, we identified MDC1, a key checkpoint protein involved in the cellular response to DNA double-strand breaks, as a TopBP1-associated protein. The specific TopBP1–MDC1 interaction is mediated by the fifth BR...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080258/ https://ncbi.nlm.nih.gov/pubmed/21482717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010026 |
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