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Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling
The spatiotemporal regulation of E-cadherin expression is important during body plan development and carcinogenesis. We found that Tara (Trio-associated repeat on actin) is enriched in cadherin-based adherens junctions (AJs), and its knockdown in MDCK cells (Tara-KD cells) significantly decreases th...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080255/ https://ncbi.nlm.nih.gov/pubmed/21482718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009100 |
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