Retromer terminates the generation of cAMP by internalized PTH-receptors

Generation of cAMP by G protein–coupled receptors (GPCRs) and its termination is currently thought to occur exclusively at the plasma membrane of cells. Under existing models of receptor regulation, this signal is primarily restricted by desensitizationof the receptors through their binding to β-arr...

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Bibliografiske detaljer
Main Authors: Feinstein, Timothy N., Wehbi, Vanessa L., Ardura, Juan, Wheeler, David S., Ferrandon, Sebastien, Gardella, Thomas J., Vilardaga, Jean-Pierre
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079799/
https://ncbi.nlm.nih.gov/pubmed/21445058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.545
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