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Sustained cyclic AMP production by parathyroid hormone receptor endocytosis

Cell signaling mediated by the G protein-coupled parathyroid hormone receptor type 1 (PTHR) is fundamental to bone and kidney physiology. It has been unclear how the two ligand systems—PTH, endocrine and homeostatic, and PTH-related peptide (PTHrP), paracrine—can effectively operate with only one re...

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Autors principals: Ferrandon, Sébastien, Feinstein, Timothy N, Castro, Marian, Wang, Bin, Bouley, Richard, Potts, John T, Gardella, Thomas J, Vilardaga, Jean-Pierre
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032084/
https://ncbi.nlm.nih.gov/pubmed/19701185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.206
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