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Sustained cyclic AMP production by parathyroid hormone receptor endocytosis
Cell signaling mediated by the G protein-coupled parathyroid hormone receptor type 1 (PTHR) is fundamental to bone and kidney physiology. It has been unclear how the two ligand systems—PTH, endocrine and homeostatic, and PTH-related peptide (PTHrP), paracrine—can effectively operate with only one re...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032084/ https://ncbi.nlm.nih.gov/pubmed/19701185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.206 |
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