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Transcriptional Regulation of Estrogen Receptor-α by p53 in Human Breast Cancer Cells

Estrogen receptor α (ER) and p53 are critical prognostic indicators in breast cancer. Loss of functional p53 is correlated with poor prognosis, ER negativity and resistance to antiestrogen treatment. Previously, we found that p53 genotype was correlated with ER expression and response to tamoxifen i...

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Detalhes bibliográficos
Main Authors: Shirley, Stephanie Harkey, Rundhaug, Joyce E., Tian, Jie, Cullinan-Ammann, Noirin, Lambertz, Isabel, Conti, Claudio J., Fuchs-Young, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079369/
https://ncbi.nlm.nih.gov/pubmed/19351845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3628
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