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Dynamic role of the codon 72 p53 single-nucleotide polymorphism in mammary tumorigenesis in a humanized mouse model

Female breast cancer (BrCa) is the most common noncutaneous cancer among women in the United States. Human epidemiological studies reveal that a p53 single-nucleotide polymorphism (SNP) at codon 72, encoding proline (P72) or arginine (R72), is associated with differential risk of several cancers, in...

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Publicat a:Oncogene
Autors principals: Gunaratna, Ramesh T., Santos, Andres, Luo, Linjie, Nagi, Chandandeep, Lambertz, Isabel, Spier, Madison, Conti, Claudio J., Fuchs-Young, Robin S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756019/
https://ncbi.nlm.nih.gov/pubmed/30651598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0630-4
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