Paracrine Overexpression of Insulin-Like Growth Factor-1 Enhances Mammary Tumorigenesis in Vivo

Insulin-like growth factor-1 (IGF-1) stimulates proliferation, regulates tissue development, protects against apoptosis, and promotes the malignant phenotype in the breast and other organs. Some epidemiological studies have linked high circulating levels of IGF-1 with an increased risk of breast can...

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Autori principali: de Ostrovich, Krisztina Kovács, Lambertz, Isabel, Colby, Jennifer K. L., Tian, Jie, Rundhaug, Joyce E., Johnston, Dennis, Conti, Claudio J., DiGiovanni, John, Fuchs-Young, Robin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2008
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527085/
https://ncbi.nlm.nih.gov/pubmed/18688034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071005
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