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Proteins ZNF198 and SUZ12 are down-regulated in Hepatitis B virus (HBV) X protein-mediated hepatocyte transformation and in HBV replication
Chronic Hepatitis B Virus (HBV) infection is a major etiologic factor in hepatocellular carcinoma (HCC) pathogenesis, involving effects of chronic liver inflammation and of the weakly oncogenic HBV X protein (pX). pX-mediated hepatocyte transformation requires Polo-like kinase1 (Plk1) activity, but...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079326/ https://ncbi.nlm.nih.gov/pubmed/21480320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24163 |
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